FLG2 and Alzheimer disease: To determine the significance of FLG variations for Finnish pediatric AD, we genotyped selected single-nucleotide variations (SNVs) in the FLG (n = 8) and FLG2 (n = 6) genes and tested their association with AD using Fisher’s exact test (Løset et al., 2019) and Benjamini−Hochberg false discovery rate correction for multiple testing (Benjamini and Hochberg, 1995).