TNF and non-small cell lung carcinoma: Yehia et al. found that TNF-α polymorphisms (rs1800629; −308 G/A) were positively associated with pancreatic and non-small cell lung cancer cohorts through a study of pancreatic and non-small cell lung cancer cohorts; conversely, (rs1799964; -1031T/C) may act as a protective factor against cachexia in patients with non-small cell lung cancer (34).