Significant downregulation of the miR-200 family, which consists of miR-141, miR-200a, miR-200b, miR-200c, and miR-429, regulates the expressions of mesenchymal markers ZEB1, ZEB2, TWIST1, TWIST2, Snai1, and Snai2 and promotes EMT in breast cancer (Bockmeyer et al., 2011). The gene discussed is TWIST2; the disease is breast carcinoma.