Within COVID-19 patients, prolonged inflammation against the virus is considered to be a remarkable factor for the progression of the disease and mortality, and it is associated with the elevated degree of cytokines in circulation, extreme lymphopenia, and severe penetration of mononuclear cells into the lungs, heart, kidneys, spleen and lymph nodes as well as significantly increased C-reactive protein (CRP), Pentraxin-3, serum ferritin, and D-Dimers (Felsenstein et al., 2020; Harrison et al., 2020; Merad and Martin, 2020; Brunetta et al., 2021; Genc AB et al., 2021). The gene discussed is CRP; the disease is COVID-19.