Additionally, ribosomal protein-encoding genes (RPLP1, RPLP2, RPS2, RPL39, RPS24, and RPL41), cytoskeleton-related genes (TMSB4X, ACTB, ACTG1, TMSB10, CFL, and VIM), and some angiogenesis-related genes were upregulated in cluster 8 ECs (Figure 6D), indicating that the cells may be involved in promoting tumor growth and protein synthesis. Here, VIM is linked to neoplasm.