Tumor-suppressing gene sets (RPL4, RPLP1, RPL18A, RPL32, RPL13, RPL39, RPL37, RPS2, and RPS27) suppressed tumor protein synthesis, enforced p53 signaling, induced tumor cell senescence, reduced tumor cell viability and proliferation, and inhibited tumor development (Xiong et al., 2011; Kardos et al., 2014; Cho et al., 2020). The gene discussed is RPS27; the disease is neoplasm.