The subpopulation of cells with high expression of BIRC3 was involved in tumor suppressive regulatory role (Andersen et al., 2017; Nakamizo et al., 2021), while IRF7 recruited activated inflammatory cells producing interferons (Tomasello et al., 2018; Zhang et al., 2021d; Somebang et al., 2021). The gene discussed is BIRC3; the disease is neoplasm.