TAFAZZIN and dilated cardiomyopathy: Mouse strain dependent perinatal lethality of the Taz gKO mice and low body weight limits the mouse model for studying Taz function and CL remodeling to understand BTHS cardiac dysfunction (Wang et al, 2020, 2023; Liu et al, 2021) Nevertheless, the tissue specific deletion of Taz revealed important aspects of BTHS, including the development of dilated cardiomyopathy and substantially reduced fractional shortening (Wang et al, 2020).