We found some of the genes significantly correlated between GBM models that were exclusive to either PDXs or cell lines were transcription factors, including DACH2, ELK3, FEV, GTF2H2B, KLF10, MAFK, REST, SALL4P5, and TFB1M, specific to PDXs and HSFX4, HSFY8P, MITF, MYCN, SP2, and YY2, specific to cell lines. This evidence concerns the gene REST and glioblastoma.