The pathological diagnosis was anaplastic oligodendroglioma (WHO grade III), with IDH1:p.R132H, PIK3R1:p.G376R, CIC:p.N205S, and FUBP1:p.Y505Gfs*16 mutations confirmed as driver genes in tumor tissue. The gene discussed is PIK3R1; the disease is anaplastic oligodendroglioma.