In the ALK− ALCL group, higher expression of IFN-γ, IL-8, IL-10, IL-17, IL-23, IP-10, MCP-1, MIP-1β, and RANTES were associated with shorter OS, while IFN-γ, IL-8, and RANTES had a further association with a lower CR rate, which indicated that the recruitment of tumor-associated macrophages (TAMs) may be involved in the lymphomagenesis [48]. The gene discussed is IFNG; the disease is anaplastic large cell lymphoma.