SSPN and atrial fibrillation: The locus FOXC1 for coronary artery disease, USP39 for myocardial infarction, and SLC35F1 and SSPN for atrial fibrillation were significantly (P < 1.01 × 10−4) and concordantly associated with their respective outcomes in both cohorts while not reaching genome-wide significance in either one of the outcome cohorts (Supplementary Data 31).