Hyperglycemia frequently occurs incritically ill patients and is considered potentially toxic, as it increases therisk of inflammatory and thrombotic events that can contribute to the occurrence ofmultiple organ and system dysfunction and mortality.32 The potential benefits of insulin infusion for glycemic control have beendemonstrated in studies conducted with critically ill patients, including olderpeople, which have undoubtedly contributed to the prescription of this PIM.33,34. The gene discussed is INS; the disease is Hyperglycemia.