We also made similar observations on MAPK4 enhancing PDK1 protein levels in human non-small cell lung cancer H1299 and H157 cells, colorectal cancer HCT116 cells, and prostate cancer DU145 cells (S5 Fig), suggesting the MAPK4-PDK1 axis beyond TNBC. This evidence concerns the gene PDK1 and non-small cell lung carcinoma.