Second, other groups and ours have identified some hepatoblastoma susceptibility loci in the myeloperoxidase [6], and CCND1 [7], xeroderma pigmentosum, complementation group C (XPC) [8], methyltransferase-like 14 (METTL14) [9], METTL3 [10], METTL1 [11], high mobility group AT-hook 2 (HMGA2) [12], tRNA (guanine-N(7)-)-methyltransferase subunit WD repeat domain 4 (WDR4) [13], YTH N6-methyladenosine RNA-binding protein F1 (YTHDF1) [14], and WT1-associated protein (WTAP) [15] genes using the candidate gene method. The gene discussed is METTL3; the disease is hepatoblastoma.