Bevacizumab is thought to be most effective when tumor cell growth is directly dependent on VEGF-signal,27 and in some cases of the serous type, cancer cells have been reported to express high levels of VEGF receptors.34,35 In other words, differences in dependence on VEGF among histologic subtypes may be associated with the effectiveness of bevacizumab. Here, VEGFA is linked to neoplasm.