The lymphoma had a striking LBCL-like morphology; the neoplastic cells were strongly positive for CD30 and CD15, showed markedly diminished expression of the B cell program (negativity for CD20, CD79a, OCT2, BOB1, and CD19) (Fig. 4B), as well as for CD45, CD23, and PDL1. Here, TNFRSF8 is linked to lymphoma.