PDLIM7 and neoplasm: EBV offers an attractive, druggable nonhost target, but is predominantly latent in infected tumor cells, and most of the ∼80 protein-coding viral genes are epigenetically silenced, except for a small subset that is necessary for the maintenance and replication of the episome (EBNA1), to drive host cell proliferation, and to block apoptotic pathways (LMP-1, LMP-2A).28