Cuproptosis-related lncRNA AC099850.3 is a prognostic marker for hepatocellular carcinoma (HCC) and has been confirmed to promote HCC progression via the PRR11/PI3K/AKT axis (Wang et al., 2021; Pak et al., 2022; Zhong et al., 2022). Here, PRR11 is linked to hepatocellular carcinoma.