BMP signalling has both tumor-promoting as well as -suppressing effects: at the same time that BMP4 is an important regulator of cell migration and invasion and induces epithelial–mesenchymal transition (EMT), an event that is crucial for the ability of cancer cells to acquire mobility and eventually metastasize, BMP4 can promote anti-tumor effects (127). The gene discussed is BMP4; the disease is neoplasm.