These molecular markers include ADAMTS6, MMP-9, TIMP-1, MCM7, ALK7, PTTG1, CUL4A, PITX1, SCN3B, USP8, CRMP1, CCNB1, CENPE, HMGA2, POU6F2, CDKN2A, Galectin-3, DGKZ, VEGF, Rb, and ASK; which were all found to be significantly associated with tumor aggressiveness and invasiveness (24–27, 30, 31, 35–37, 39, 41, 43, 44, 48–50, 53, 54, 58, 65–68). This evidence concerns the gene ACVR1C and neoplasm.