detected cervical biopsy specimens from 148 normal women, 48 patients with cervical cancer (CC) and 38 patients with cervical intraepithelial neoplasia (CIN), and found that H19 methylation levels in CIN and CC groups were low and highly expressed, which would increase HPV susceptibility and the risk of invasive CC and CIN (13). Here, H19 is linked to cervical squamous intraepithelial neoplasia.