AKT1 and hepatocellular carcinoma: MCM7 inhibition led to a decrease in the esophagus (Qiu et al., 2017) and hepatocellular carcinomas (Qu et al., 2017) viability, colony-forming ability, and migration capacity due to reducing phosphorylation of AKT1 and mTOR proteins with decreasing CDK1, CCNE1, and CCNE2 expression levels (Qiu et al., 2017).