Conversely, inhibition of autophagy by Baf-A1, chloroquine, 3MA, or knockdown of LC3B or p62 markedly increased apoptosis in leukemia cells treated with AraC at concentrations of 3.2 or 10 μM (Bosnjak et al., 2014; Cheong et al., 2016). Here, SQSTM1 is linked to leukemia.