Among these genes, CRK, CRKL, EGF, EGFR, ERBB2, GRB2, GSK3B, HRAS, JUN, MAP2K1, MAPK1, MAPK10, MAPK3, MAPK8, MAPK9, MYC, PAK1, PAK2, PAK7, PIK3CA, PIK3CD, PIK3CG, PIK3R1, PIK3R2, PIK3R3, PIK3R5, PRKCA, PRKCB, PRKCG, PTK2, RAF1, RHOA, RPS6KB1, SHC1, SHC3, SOS1, SOS2, SRC, THBS1 genes can be potential T2D causing genes. The gene discussed is RPS6KB1; the disease is type 2 diabetes mellitus.