MUC5AC and colorectal adenocarcinoma: However, previous reports have described that traditional human colorectal adenocarcinoma cell lines, such as SW480, Caco-2 and HT-29, do not exhibit normal intestinal epithelia physiology, as they are characterized by the absence of cellular diversity, low mucin synthesis, and differences in TEER values, compared to their in vivo counterparts [34, -36].