GAD1 and irritable bowel syndrome: In the LD-score regression analysis, IBS showed significant (P < 0.0001) genetic correlations with GAD (rg = 0.49), MD (rg = 0.55), BIP (rg = 0.13), SCZ (rg = 0.17), and DVD (rg = 0.38), but not for IBD (rg = -0.01).