Prognostic analysis of METTL1/WDR4 in HCC patients included Overall Survival (OS), Disease-Specific Survival (DSS), Progress Free Interval (PFI), and univariate/multifactorial Cox regression analysis.In the ICGC cohort, HCC samples containing survival time (n = 231), survival status (n = 231), age (n = 261), gender (n = 261), and tumor stage (n = 261) were retained. The gene discussed is WDR4; the disease is hepatocellular carcinoma.