Multivariable analysis in the above cohorts showed that TRIB1 gene expression correlated with worse overall survival independent of clinical variables (TCGA GBM: HR 1.181 (1.37–1.017), p = 0.029 ad TCGA LGG: HR 1.786 (2.617–1.219, p = 0.003) Tables 1 and 2 respectively). This evidence concerns the gene TRIB1 and glioblastoma.