Atherosclerosis plaque size and composition were no longer different between Ldlr-/-Cd36-/-Card9+/+and Ldlr-/-Cd36-/-Card9-/- chimeric groups (Fig. 7I, K), indicating that increased expression of CD36 was directly responsible for increased atherosclerosis in Card9-deficient animals. Here, LDLR is linked to atherosclerosis.