Regarding the diagnosis in the specific pathology of NSCLC, the combined detection of the 4-lncRNA (RMRP, NEAT1, TUG1, and MALAT1) panel with traditional tumor markers obtained AUCs of 0.85 for adenocarcinoma and 0.93 for SCC[114] Similarly, Xie et al. reported the expression profile of serum lncRNA in NSCLC and further proposed a diagnostic lncRNA panel consisting of SOX2OT, ANRIL, CEA, CYFRA21‐1, and SCCA, with an AUC of 0.853 in diagnosing NSCLC [116]. This evidence concerns the gene SERPINB3 and adenocarcinoma.