B2M and central nervous system cancer: Furthermore, we also analyzed the RNA‐seq data of cohort GSE167514 (human RCC cell lines 786O transfected with GDH1‐shRNA and Control‐shRNA) and GSE121580 (human glioma cell lines U87 transfected with GDH1‐shRNA and Control‐shRNA).[13] Consistently, antigen presentation and processing pathways were enriched and B2M was elevated in the ShNT group with higher αKG levels (Figure S1C‐G, Supporting Information).