Exome sequencing and other approaches have further shown that mutations in RPL5 (uL18), RPL10 (uL16), RPL11 (uL5), RPL22 (eL22), RPS15 (uS19) and RPS20 (uS10) are present in a variety of cancers, especially leukaemia (34,35). This evidence concerns the gene RPL22 and cancer.