Our findings revealed a statistically significant co-prevalence of several co-morbidities among T2DM patients in the MENA region, including angina, cerebrovascular accident, CAD, CHD, heart disease, peripheral vascular disease, hypertension, hyperlipidemia, abnormal lipid profile, ESRD, renal impairment, overweight, central abdominal obesity, stroke, poor glycemic control presenting as HbA1c abnormal levels, and macro albumin abnormal levels. This evidence concerns the gene ALB and heart disorder.