To test GVL activity of STAT3–/– T cells, irradiated BALB/c mice were inoculated i.p. with luciferase-transfected BCL1 (BCL1/Luc+) leukemia/lymphoma cells (625 × 103) and then engrafted with TCD-BM alone or TCD-BM plus STAT3–/– Thy1.2+ T cells (2.5 × 106). This evidence concerns the gene CCND1 and leukemia.