MEG3 and central nervous system cancer: Silencing of the MEG3 gene significantly reduced cell migration in U87MG glioma at 48 (p < 0.001) and 72 (p = 0.010) hours of analysis (Figure 2A) and at 24 (p < 0.001), 48 (p < 0.001) and 72 (p < 0.001) hours of analysis in HUVEC cells (Figure 2B).