The spectrum of long-term low-grade epilepsy-associated brain tumors is expanding rapidly and, in addition to DNTs, includes diffuse astrocytoma MYB or MYBL1-altered polymorphous low-grade neuroepithelial tumor of the young (PLNTY), diffuse low-grade glioma, MAPK pathway-altered tumor, and so on [5]. This evidence concerns the gene MYBL1 and diffuse astrocytoma.