CD8A and neoplasm: Finally, CD8+ T cell migration was increased when we used conditioned medium from tumor neutrophils treated with rm-IL-17A as compared to conditioned medium from rm-IL-17A-treated melanoma cells alone (P = 0.0340), while CD8+ T cell migration remained at a similar level when conditioned media from untreated melanoma cells versus untreated tumor neutrophils were used (P = 0.8283; Fig. 4f).