Emerging evidence suggests that Schwann cells promote cancer cell metastasis by secreting C-X-C Motif Chemokine Ligand 5 (CXCL5), Interleukin 6 (IL-6), and Transforming Growth Factor Beta 1 (TGF-β), or by direct cancer cell contact26–29. This evidence concerns the gene CXCL5 and cancer.