Tumors with discordant read pairs supporting viral integration were associated with lower expression of sky blue (NF-κB) module genes, (Fig. 5C and SI Appendix, Fig. S4C) Taken together, these results demonstrate that tumor subclasses defined by the sky blue (NF-κB) module are associated with a lack of viral genomic integration and a distinct pattern of viral gene expression. Here, NFKB1 is linked to neoplasm.