α5 integrin– positive cells represented more than 40% of the myeloid cells (CD11b+) in ALS patient cervical spinal cord (48.5 ± 10.8%, n = 3) and motor cortex (42.8 ± 4.9%, n = 3), without significant differences between the two regions (SI Appendix, Fig. S2 A and B). The gene discussed is ITGAM; the disease is amyotrophic lateral sclerosis.