NFATC3 and pulmonary fibrosis: NFATc3+/- mice that received NFATC3+/+ pulmonary macrophages by adoptive transfer or recombinant mouse CXCL2 alone showed increased pulmonary fibrosis severity and fibrotic gene expression similar to wild-type (NFATC3+/+) mice, suggesting a pivotal role for NFATc3 in the development of lung fibrosis.