MSH6 and cervical carcinoma: Germline P/LP variants in MMR genes (MLH1, MSH2, MSH6, and PMS2) were detected in 28.6% (4 of 14), 20.9% (9 of 43), and 14.3% (1 of 7) of high microsatellite instability (MSI-H) ovarian, endometrial, and cervical cancer, respectively (Figure 3B).