SOD2 and neoplasm: For example, SNP rs5746136 (G > A) may influence m6A to modify and regulate SOD2 expression in bladder cancer by directing the binding of HNRNPC to SOD2, which is a tumor suppressor [102]; SNP rs7495G could promote HNRNPC expression in a miRNA-mediated manner, which puts pancreatic ductal adenocarcinoma at increased risk [103]; The novel SNP rs9906944 (C > T) in IGF2BP1 was significantly associated with a reduced risk of gastric cancer at discovery stage [104].