For example, IL‐1β, IL‐1RA, IL‐6, IL‐18, GROα associated with intrinsic immunity and neutrophils; VEGF‐A, IL‐10 associated with angiogenesis; IFN‐γ, TNF‐α, IL‐12 associated with Th1; PCT associated with sepsis, etc. Some studies have shown that these cytokines are also involved in the pathogenesis of psoriasis.1 The gene discussed is IL18; the disease is psoriasis.