EGFR and acne: From the first group of terms for the trend analysis, the following acne type terms were selected: “facial acne,” “acne conglobate,” “chloracne,” “atrophic acne,” and “acne pustulosis.” We divided the second group of terms into subgroups: “acne and antibiotics,” “acne and retinoids,” “acne and anti-inflammatory drugs,” and “acne and photodynamic therapy.” From the third group of terms, we chose the following: “acne and the epidermal growth factor receptor (EGFR) inhibitors (EGFRis),” and “acne and comorbidities.”