CD274 and cancer: In addition, new findings in the literature suggestthat DTX may also increase the expression of PD-L1 in cancer cells,which means making target cells more sensitive to PD-L1 mAbs likeDVL.57 According to the results, the HSA-DTX@PEG-DVLNPs effectively deliver DTX to tumor cells, causing a cytotoxic effectrate of up to 70% on both TNBC cells at 72 h and increasing cell apoptosis(Figure 3).