EGFR and neoplasm: Because of the retrospective nature of the data collection and the failure to include some known prognostic parameters such as tumor cell differentiation, vascular invasion, and perineural invasion, and some important molecular factors (such as EGFR mutation, ALKEML4 fusion), more rigorous prospective studies are needed to validate, and further efforts are required to improve this model in terms of wider geographic recruitment and integration of some other factors.