The receiver-operating characteristic curve analysis revealed the following cutoffs: age of 70.5 years (sensitivity, 30.5%; specificity, 90.5%; AUC, 0.652), serum NGAL of 146.9 ng/ml (sensitivity, 55%; specificity, 75.9%; AUC, 0.674), history of cerebrovascular disease (sensitivity, 46.1%; specificity, 79.6%; AUC, 0.628), male sex (sensitivity, 67.7%; specificity, 48.9%; AUC, 0.583), and diabetes (sensitivity, 34.8%; specificity, 83.9%; AUC, 0.593). This evidence concerns the gene LCN2 and cerebrovascular disorder.