Consistent with our scRNA-seq results, miR-138-5p, miR-200c and combo treatment all decreased the mean PD-L1 intensities in TIME by 28.8% (P=0.1062), 43.1% (P=0.0155) and 81.9% (P<0.001), respectively, as compared with tumor tissue from control mice (Figure 4I). Here, CD274 is linked to neoplasm.