Also, recently, Valin et al. (2022) reported JUN, an oncogenic transcription factor, as a regulator of glycolytic metabolism in AML, since it increases the expression of hexokinase I (HKI) and HKII, glucose phosphate isomerase (GPI), phosphofructo-1-kinase (PFKP), aldolase A (ALDOA), glyceraldehyde-3-phosphate dehydrogenase (GAPDH), phosphoglycerate kinase (PGK1), enolase 1 (ENO1), and PKM. The gene discussed is HK2; the disease is acute myeloid leukemia.