For a more in-depth understanding, we evaluated interleukins IL-1 β, IL-6, tumour necrosis factor-a (TNF-a), catalase (CAT), glutathione (GSH), superoxide dismutase (SOD), malondialdehyde (MDA), prostaglandin E2, myeloperoxidase (MPO), alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and nuclear factor erythroid 2-related factor (Nrf2) in CFA-induced arthritis model. Here, TNF is linked to arthritic joint disease.